Kidney Disease Management: A Practical Approach for the Non-Specialist Healthcare Practitioner 1st Edition

Kidney Disease Management: A Practical Approach for the Non-Specialist Healthcare Practitioner 1st Edition

Toxicology is the study of the adverse effects of chemical, physical, or biological agents on people, animals, and the environment. Toxicologists are trained to investigate, interpret, and communicate the nature of those effects.

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Over the last ten years the subject of toxicology has changed dramatically, moving from a discipline which was once firmly wedded to traditional methods to one which is keen to embrace the innovative techniques emerging from the developing fields of cell culture and molecular biology. There is an acute need for this to be reflected in a paradigm shift which takes advantage of the opportunities offered by modern developments in the life sciences, including new in vitro and in silico approaches, alternative whole organism (non–mammalian) models and the exploitation of omics methods, high throughput screening (HTS) techniques and molecular imaging technologies.

This concise, accessible introduction to the field includes the very latest concepts and methodologies. It provides MSc, PhD and final year undergraduate students in pharmacy, biomedical and life sciences, as well as individuals starting out in the cosmetics, consumer products, pharmaceutical and testing industries, with everything they need to know to get to grips with the fast moving field of toxicology and the current approaches used in the risk assessment of drugs and chemicals.

Kidney Disease Management: A Practical Approach for the Non-Specialist Healthcare Practitioner 1st Edition

by Rachel Lewis (Editor), Helen Noble (Editor)

ISBN-13: 978-0470670613
ISBN-10: 0470670614

Kidney Disease Management: A Practical Approach for the Non-Specialist Healthcare Practitioner 1st Edition Contents

Contributors vii
Foreword xi
David Colin-Thomé
Foreword xii
Rosemary Macri
Introduction: Managing Patients with Chronic Kidney Disease
in Non-Specialist Areas: a Chronic Illness Approach xiii
Rachel Lewis
1 Managing Chronic Conditions: The Policy Context 1
Beverley Matthews
2 What Non-Specialists Need to Know about Chronic
Kidney Disease 12
Graham Woodrow, Jeanette Denning and David Lewis
3 A Practical Approach to Chronic Kidney Disease
in Primary Care 31
Hugh Rayner, Rajib Pal and Indranil Dasgupta
4 General Considerations Related to Treatment Modalities 52
Aisha I. Geeson, Charles R. V. Tomson and Lesley Lappin
5 Psychosocial Aspects of Living with Chronic Kidney Disease 76
Emma Coyne
6 Acute Kidney Injury in Hospitalised Patients 101
Keith Harkins, Rachel Lewis and Rachel Hilton
7 Management of Patients with or at Risk of Kidney Disease
on the Surgical Ward 122
Colin H. Jones and Maggie Higginbotham
8 Medication Management and Chronic Kidney Disease 143
Aileen Dunleavy
vi Contents
9 Optimising Nutrition in People with Chronic Kidney Disease 169
Helena Jackson and Sally Noble
10 Supportive and Palliative Care for Patients with
Advanced Kidney Disease 194
Sheila Johnston, Helen Noble and Rachel Lewis
Index 213
vii

Kidney Disease Management: A Practical Approach for the Non-Specialist Healthcare Practitioner 1st Edition Contributors

David Colin-Thomé Dr David Colin-Thomé is an independent healthcare consultant and former general practitioner at Castlefields in Runcorn. He also spent several years as the National Clinical Director of Primary Care and clinical lead for the long-term conditions programme, Department of Health, England.

Emma Coyne BSc(Hons), ClinPsyD Dr Emma Coyne is a clinical psychologist working within the adult renal unit
at Nottingham University Hospitals NHS Trust. She is particularly interested in improving psychological care using compassion-based interventions. She also has a special interest in improving services and provision for young
adults with CKD. Indranil Dasgupta MBBS, MD, DM, FRCP Indranil Dasgupta is a consultant physician and nephrologist at Birmingham Heartlands Hospital and honorary senior lecturer at the School of Clinical and
Experimental Medicine, University of Birmingham.

His main areas of interests are hypertension, chronic kidney disease, pre-dialysis care and renal bone disease.
Jeanette Denning RGN Jeanette Denning is a senior sister in peritoneal dialysis and pre-dialysis pathway at the Leeds Teaching Hospitals NHS Trust. Aileen Dunleavy MRPharmS (Ipresc) Aileen Dunleavy is senior renal pharmacist at Crosshouse Hospital, Kilmarnock. She is co-editor of the Renal Drug Handbook and has been a renal pharmacist for 18 years. She is a pharmacy prescriber and has an interest in the management of anaemia.

Aisha I. Geeson MBChB, MRCP Dr Aisha Geeson graduated from Dundee Medical School in 2006 and has
worked in Edinburgh, Swansea and Bristol. She is currently a specialist registrar in renal medicine at Southmead Hospital, Bristol, having developed her interest in renal medicine while working in Morriston Hospital, Swansea.
Keith Harkins MBChB, MRCP Dr Keith Harkins is a consultant physician and geriatrician at Wythenshawe Hospital, University Hospital of South Manchester. Within elderly care Dr Harkins is particularly interested in rehabilitation, continence and end-of-life care.

viii

Contributors Maggie Higginbotham BSc (Hons) Maggie Higginbotham is a renal specialist nurse currently working as clinical educator in York Renal Services. She qualified as a registered nurse in 1987, and began renal nursing in 1988 at St James’s Hospital, Leeds, before moving to York Renal Services in 1999. She has recently completed a BSc in healthcare practice at the University of Leeds. Maggie is passionate about providing a high standard of multi-professional care to renal patients and their families and has a keen interest in ‘user involvement’.

Rachel Hilton MA, PhD, FRCP Dr Rachel Hilton received her BA at the University of Oxford in 1985 (physiological sciences) and her BM BCh in 1988. She has been a consultant nephrologist at Guy’s and St Thomas’ NHS Foundation Trust since 1999, and was lead clinician in nephrology between 2003 and 2008. She has held an honorary appointment in the School of Medicine at King’s College London since 2006. She is currently R&D theme lead for transplantation and medical lead in transplantation.

Dr Hilton is interested in renal transplantation, living kidney donation, viral infection after transplantation, autoimmune diseases, renal disease in pregnancy and renal disease in patients with human immunodeficiency virus.
Helena Jackson BSc (Hons), PgDip, MSc, RD Helena Jackson is a renal dietitian at St George’s Hospital, London. She has worked as a renal dietitian since 1995 in all areas of renal dietetics, from enteral and parenteral feeding to optimising patient motivation and understanding of diet. She is the co-author of two books on diet for patients with
chronic kidney disease. Sheila Johnston RN, MSc, BSc Sheila Johnston is the lead nurse, clinical lead in chronic kidney disease (CKD) at the Royal Free London NHS Foundation Trust.

She has been working within the renal specialty since 1995 and moved into specialist practice in CKD in 2003. She has a particular interest in the supportive and palliative care needs of those patients opting not to have dialysis, and in further developing shared decision making in this group to enhance their end-of-life care. Colin H. Jones MBChB, MD, FRCP, MEd (ClinEd) Dr Colin Jones is a consultant physician and nephrologist at York Teaching Hospital NHS Foundation Trust. He qualified in 1988 (University of Birmingham), was awarded a Doctor of Medicine degree in 1999 (University of Birmingham) and a Master’s in Education in 2008 (University of Leeds). He strongly believes
in providing holistic patient-centred care delivered through evidence-based medicine and supported by robust audit and governance mechanisms.

He is actively involved in clinical research and in undergraduate and postgraduate education. Lesley Lappin, RN, BSc (Hons), MSc Lesley Lappin is a clinical nurse specialist and community dialysis lead at Salford Royal NHS Foundation Trust. She has worked in kidney care for  Contributors ix 23 years and is the nursing lead for the peritoneal dialysis service at Salford Royal Hospital. In 2010 she was awarded a Kidney Research/BRS joint fellowship and is studying for a doctorate in quality improvement sustainability. David Lewis MBChB, MD, FRCP
Dr David Lewis is a nephrologist and general physician. He is the clinical lead for peritoneal dialysis at Salford Royal NHS Foundation Trust and has a particular interest in multidisciplinary working. Rachel Lewis RN, RSCN, MSc, MA (Econ), BA (Hons) Rachel Lewis is a nurse practitioner at Manchester Business School engaged in health services research in general practice. She previously worked as a community matron and is interested in care integration and service delivery for people with multiple chronic conditions. She has spent many years working in adult and children’s renal services, and worked for several years as a nurse adviser to the Department of Health, working with the renal and pathology policy teams.

Rosemary Macri Rosemary Macri is the Chief Executive of the British Kidney Patient Association (BKPA). Rosemary first worked with the BKPA in 1977 and became a personal assistant to the founder president. Following a break to pursue other opportunities she returned to the charity in 2002, and in 2008 became its Chief Executive. The BKPA provides advice, support and financial help for people with kidney disease.

Beverley Matthews RN Beverley Matthews is the director of NHS Kidney Care and Liver Care. Originally a nurse, she has worked for many years in renal services as a transplant coordinator and a network manager. NHS Kidney Care aims to improve the outcomes for people with kidney disease, and achieves this by helping to embed evidence-based innovations in everyday practice.

Helen Noble RN, PhD, BSc, PG Dip Academic Practice Dr Helen Noble is a lecturer in Health Services Research at Queen’s University Belfast. Previously she worked as a ward manager, matron and then as a senior clinical nurse specialist involved in setting up one of the first renal palliative and supportive care programmes in the UK. She has research expertise in nephrology nursing, particularly related to those who opt not to embark on dialysis, and their carers, and is interested in developing interventions to support this group. Sally Noble APD, BA Sally Noble has worked as a specialist renal dietitian in both Australia and the United Kingdom. She is currently working as a senior renal/diabetes dietitian in Brisbane, Australia. She is interested in promoting healthy balanced diets for people with kidney disease to prevent and manage their condition, as well as investigating ways to screen and manage patients with poor nutrition….

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